Recent papers published from our lab

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes.
Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY.  Nature. 2010 Nov 11;468(7321):263-9.


Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.
Xue M, Craig TK, Shin OH, Li L, Brautigam CA, Tomchick DR, Südhof TC, Rosenmund C, Rizo J.  PLoS One. 2010 Sep 2;5(9). pii: e12544.


Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity.
Xue M, Craig TK, Xu J, Chao HT, Rizo J, Rosenmund C.  Nat Struct Mol Biol. 2010 May;17(5):568-75. Epub 2010 Apr 18.


Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.
Shin OH, Lu J, Rhee JS, Tomchick DR, Pang ZP, Wojcik SM, Camacho-Perez M, Brose N, Machius M, Rizo J, Rosenmund C, Südhof TC.  Nat Struct Mol Biol. 2010 Mar;17(3):280-8. Epub 2010 Feb 14.


Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila Complexins orchestrates synaptic vesicle exocytosis.
Xue M, Lin YQ, Pan H, Reim K, Deng H, Bellen HJ, Rosenmund C. Neuron. 2009 Nov 12;64(3):367-80.

Highlighted in F1000 as exceptional


The headache of a hyperactive calcium channel.
Xue M, Rosenmund C. Neuron. 2009 Mar 12;61(5):653-4.


Synaptic vesicle fusion.
Rizo J, Rosenmund C. Nat Struct Mol Biol. 2008 Jul;15(7):665-74.